CREST Syndrome

Calcinosis Cutis in CREST Syndrome

Calcinosis cutis is a term used to describe a group of disorders in which calcium deposits form in the skin and classified as metastatic, dystrophic, idiopathic and iatrogenic. The present case has calcinosis cutis with features of Raynaud’s phenomenon, oesophageal dysmotility, sclerodactyly and telangiectasia (CREST syndrome) the patients with CREST syndrome often have better prognosis than di...

Primary biliary cirrhosis and CREST syndrome.

of the skin folds of her face and a lack of ability to open her mouth. Her limbs showed sclerodactyly and isolated telangiectases (Fig. 1a). She had positive anticentromere antibody. She was evaluated because of dysphagia with solids, pyrosis and regurgitation. The esophageal manometry showed a hypotensive lower esophageal sphincter and peristaltic waves of low amplitude in the body of the esop...

Oral medicine case book 62: CREST syndrome.

The CREST syndrome--successful reduction of pulmonary hypertension by captopril.

A patient with severe pulmonary hypertension due to pulmonary arteriolar obliteration complicating a long standing CREST variant of systemic sclerosis showed improvement in cardiac output and exercise tolerance during treatment with captopril, which was discontinued because of persistent systemic hypotension. It is suggested that captopril would have a useful and possible prophylactic effect ea...

Large vessel occlusive disease associated with CREST syndrome and scleroderma.

OBJECTIVES To report the cases of three patients with CREST syndrome and one patient with diffuse scleroderma who had severe macrovascular disease and only minimal vascular risk factors. METHODS The medical histories, physical examinations, and results of clinical investigations were reviewed in four patients. RESULTS These four patients had severe morbidity from macrovascular disease of th...